The Attack opens with Amin Jaafari, an Israeli surgeon of Palestinian origin, trying to save the casualties of a suicide bombing. A day after the deadly attack, an Israeli police officer informs Jaafari that the suicide bomber was his wife, Sihem. Believing her to be on an overnight trip, he completely refuses to accept the accusation. They were leading an ideal life in Tel Aviv, moving among both Arab and Israeli society with ease, or so Jaafari thought. But then he receives a posthumous message from Sihem confirming the worst. Desperate to understand how he missed even the slightest clue, Jaafari leaves the relative security of Israel and enters the Palestinian territories to find the fanatics who recruited her. In search of the truth, he confronts a reality that he had refused to see.